在日常生活中，无论是学习还是工作，我们常常需要撰写英文书信。一封得体的书信不仅能传递信息，还能展现个人修养与文化素养。为了帮助大家轻松应对各种场合下的书信写作，这里整理了100句英语书信的万能开头和结尾表达，供大家参考使用。

一、书信开头万能句

1. I hope this letter finds you in good health and high spirits.

2. It's been a while since we last communicated, and I thought it was time to drop you a line.

3. I am writing to express my gratitude for your recent support and assistance.

4. Dear [Name], I trust you are doing well.

5. Your letter of [date] reached me with great interest.

6. It’s always a pleasure to hear from you.

7. I’m writing to share some exciting news with you.

8. I hope you had a wonderful [holiday/festival].

9. I’ve been meaning to write to you for a long time but never got around to it.

10. Thank you for your kind invitation to [event].

二、书信结尾万能句

1. Looking forward to hearing from you soon.

2. Please let me know if there’s anything further I can assist with.

3. Feel free to reach out if you need any help or advice.

4. Wishing you all the best in everything you do.

5. Let’s stay in touch and keep in touch regularly.

6. Hoping to meet you soon and discuss this further.

7. I hope this message brings a smile to your face.

8. Please accept my heartfelt thanks for your efforts.

9. Once again, thank you for your kindness and consideration.

10. Take care and stay safe.

以上100句涵盖了书信写作中常见的开头与结尾表达方式，适用于多种场景，如正式商务函件、朋友间的问候信件以及节日贺卡等。希望大家能够根据实际需求灵活运用这些句子，写出既专业又亲切的英文书信！